Design and synthesis of novel pyrrolo[2,1-c][1,4]benzodiazepine-lexitropsin conjugates

被引：50

作者：

Damayanthi, Y ^{[1
]}

Reddy, BSP ^{[1
]}

Lown, JW ^{[1
]}

机构：

[1] Univ Alberta, Dept Chem, Edmonton, AB T6G 2G2, Canada

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1999年 / 64卷 / 01期

关键词：

D O I：

10.1021/jo9812072

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[No abstract available]

引用

页码：290 / 292

页数：3

共 34 条

[1] Solid phase synthesis of polyamides containing imidazole and pyrrole amino acids [J].

Baird, EE ;

Dervan, PB .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1996, 118 (26) :6141-6146

[2] EFFECT OF LINKER LENGTH ON DNA-BINDING AFFINITY, CROSS-LINKING EFFICIENCY AND CYTOTOXICITY OF C8-LINKED PYRROLOBENZODIAZEPINE DIMERS [J].

BOSE, DS ;

THOMPSON, AS ;

SMELLIE, M ;

BERARDINI, MD ;

HARTLEY, JA ;

JENKINS, TC ;

NEIDLE, S ;

THURSTON, DE .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1992, (20) :1518-1520

[3] RATIONAL DESIGN OF A HIGHLY EFFICIENT IRREVERSIBLE DNA INTERSTRAND CROSS-LINKING AGENT BASED ON THE PYRROLOBENZODIAZEPINE RING-SYSTEM [J].

BOSE, DS ;

THOMPSON, AS ;

CHING, JS ;

HARTLEY, JA ;

BERARDINI, MD ;

JENKINS, TC ;

NEIDLE, S ;

HURLEY, LH ;

THURSTON, DE .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (12) :4939-4941

[4] ONE-DIMENSIONAL AND TWO-DIMENSIONAL H-1-NMR, FLUORESCENCE, AND MOLECULAR MODELING STUDIES ON THE TOMAYMYCIN-D(ATGCAT)2 ADDUCT - EVIDENCE FOR 2 COVALENT ADDUCTS WITH OPPOSITE ORIENTATIONS AND STEREOCHEMISTRIES AT THE COVALENT LINKAGE SITE [J].

CHEATHAM, S ;

KOOK, A ;

HURLEY, LH ;

BARKLEY, MD ;

REMERS, W .

JOURNAL OF MEDICINAL CHEMISTRY, 1988, 31 (03) :583-590

[5] DESIGN OF SEQUENCE-SPECIFIC DNA-BINDING MOLECULES [J].

DERVAN, PB .

SCIENCE, 1986, 232 (4749) :464-471

[6] SYNTHESIS AND DNA CROSSLINKING ABILITY OF A DIMERIC ANTHRAMYCIN ANALOG [J].

FARMER, JD ;

RUDNICKI, SM ;

SUGGS, JW .

TETRAHEDRON LETTERS, 1988, 29 (40) :5105-5108

[7]

FONTANA M, 1992, ANTI-CANCER DRUG DES, V7, P131

[8]

GUO DQ, 1993, ANTI-CANCER DRUG DES, V8, P369

[9]

GUPTA R, 1995, ANTI-CANCER DRUG DES, V10, P25

[10] HYBRID MOLECULES CONTAINING PROPARGYLIC SULFONES AND DNA MINOR GROOVE-BINDING LEXITROPSINS - SYNTHESIS, SEQUENCE SPECIFICITY OF REACTION WITH DNA AND BIOLOGICAL EVALUATION [J].

GUPTA, R ;

XIE, GJ ;

LOWN, JW .

GENE, 1994, 149 (01) :81-90

← 1 2 3 4 →