Nanomaterial-based electrochemical DNA sensing strategies

被引:170
作者
Erdem, Arzum [1 ]
机构
[1] Ege Univ, Fac Pharm, Dept Analyt Chem, TR-35100 Izmir, Turkey
关键词
nanomaterials; biosensors; DNA; electrochemical transducers; nanoparticles; carbon nanotubes; guanine; adenine;
D O I
10.1016/j.talanta.2007.10.012
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
DNA sensing strategies have recently been varieted with the number of attempts at the development of different biosensor devices based on nanomaterials, which will further become DNA microchip systems. The investigations at the side of material science in connection with electrochemical biosensors open new directions for detection of specific gene sequences, and nucleic acid-ligand interactions. An overview is reported here about nanomaterial-based electrochemical DNA sensing strategies principally performed for the analysis of specific DNA sequences and the quantification of nucleic acids. Important features of electrochemical DNA sensing strategies, along with new developments based on nanomaterials are described and discussed. (c) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码:318 / 325
页数:8
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