Recoverable fluorous CBS methodology for asymmetric reduction of ketones

被引：54

作者：

Dalicsek, Z

Pollreisz, F

Gömöry, A

Soós, T

机构：

[1] Hungarian Acad Sci, Chem Res Ctr, Inst Biomol Chem, H-1525 Budapest, Hungary

[2] Hungarian Acad Sci, Chem Res Ctr, Inst Struct Chem, H-1525 Budapest, Hungary

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 15期

关键词：

D O I：

10.1021/ol051024j

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An operationally simple and recoverable fluorous CBS methodology was developed. The in situ-generated fluorous oxazaborolidine efficiently catalyzed the reduction of ketones with high enantioselectivity and reactivity. The subsequent recycling of the fluorous prolinol precatalyst was achieved by fluorous solid-phase extraction.

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收藏

页码：3243 / 3246

页数：4

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