The influence of virus structure on antibody responses and virus serotype formation

被引：167

作者：

Bachmann, MF ^{[1
]}

Zinkernagel, RM ^{[1
]}

机构：

[1] UNIV ZURICH, INST EXPT IMMUNOL, DEPT PATHOL, CH-8091 ZURICH, SWITZERLAND

来源：

IMMUNOLOGY TODAY | 1996年 / 17卷 / 12期

关键词：

D O I：

10.1016/S0167-5699(96)10066-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 [免疫学];

摘要：

Antibodies are important in protection against some primary and most secondary viral infections. However, viruses have co-evolved with the immune system and might have adapted to the host's antibody response and in some cases might even subvert it. Here, Martin Bachmann and Rolf Zinkernagel summarize evidence that B cells use repetitiveness of viral surface antigens as a marker for foreignness, which plays an important role in the evolution of host-viral relationships.

引用

页码：553 / 558

页数：6

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