Protein-protein interactions in the tetraspanin web

被引:200
作者
Levy, S [1 ]
Shoham, T [1 ]
机构
[1] Stanford Univ, Ctr Med, Dept Med, Div Oncol, Stanford, CA 94305 USA
关键词
D O I
10.1152/physiol.00015.2005
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Tetraspanins are evolutionarily conserved membrane proteins that tend to associate laterally with one another and to cluster dynamically with numerous partner proteins in membrane microdomains. Consequently, members of this family are involved in the coordination of intracellular and intercellular processes, including signal transduction; cell proliferation, adhesion, and migration; cell fusion; and host-parasite interactions.
引用
收藏
页码:218 / 224
页数:7
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