Functional implications of dendritic voltage-dependent conductances

被引：12

作者：

Crill, WE ^{[1
]}

机构：

[1] Univ Washington, Dept Physiol & Biophys, Seattle, WA 98195 USA

来源：

JOURNAL OF PHYSIOLOGY-PARIS | 1999年 / 93卷 / 1-2期

关键词：

dendrite; persistent sodium current; neocortex; pyramidal neurons;

D O I：

10.1016/S0928-4257(99)80132-6

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Layer five pyramidal neurons of rat and cat neocortex have numerous ionic conductance mechanisms. The presence of these voltage-dependent conductances in the dendrites has a significant effect on the transmission of current from synaptic sites to the spike generating region in the proximal axon. Here we show such threshold activation of persistent sodium channels markedly amplifies current flowing through glutamate activated dendritic channels. (C) Elsevier, Paris.

引用

页码：17 / 21

页数：5

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