An efficient asymmetric synthesis of (2S,3S)- and (2R,3R)-β-hydroxyornithine

被引：13

作者：

DeMong, DE ^{[1
]}

Williams, RM ^{[1
]}

机构：

[1] Colorado State Univ, Dept Chem, Ft Collins, CO 80523 USA

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 02期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/S0040-4039(00)01945-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Asymmetric syntheses of (2S,3S)- and (2R,3R)-beta -hydroxyornithine have been achieved in four steps and 46% overall yield. The key step in this synthesis involved an aldol reaction between a chiral glycine boron enolate and (3-oxo-propyl)-carbamic acid benzyl ester. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：183 / 185

页数：3

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