Increased urinary albumin excretion is a marker of risk for retinopathy and coronary heart disease in patients with type 2 diabetes mellitus

被引：39

作者：

Lunetta, M

Infantone, L

Calogero, AE

Infantone, E

机构：

[1] Univ Catania, Sch Med, Dept Internal Med, Div Metab Dis, Catania, Italy

[2] Univ Catania, Sch Med, Dept Internal Med, Div Androl, Catania, Italy

[3] Univ Catania, Sch Med, Dept Internal Med, Div Nephrol, Catania, Italy

来源：

DIABETES RESEARCH AND CLINICAL PRACTICE | 1998年 / 40卷 / 01期

关键词：

diabetes mellitus type 2; urinary albumin excretion; coronary heart disease; diabetic retinopathy;

D O I：

10.1016/S0168-8227(98)00024-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The prevalence of increased urinary albumin excretion (UAE) (micro- and macroalbuminuria) and its association with diabetic retinopathy (DR) (evaluated by fluorescent angiography), coronary heart disease (CHD), and various related risk factors were studied in 320 type 2 diabetic patients. In this subsample of type 2 diabetic patients, microalbuminuria was present in 15% of the patients; macroalbuminuria in 4.8%, CHD in 9.9%, DR in 53.4%, and arterial hypertension in 46%. UAE was independently related to CHD (P < 0.05), retinopathy (P < 0.001), hypertension (P < 0.001), and triglycerides (P < 0.02). We conclude that increased UAE is associated to a greater frequency of retinopathy and CHD in type 2 diabetic patients. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：45 / 51

页数：7

共 23 条

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