Novel DNA damage mediated by oxidation of an 8-oxoguanine residue

被引：12

作者：

Koizume, S

Inoue, H

Kamiya, H

Ohtsuka, E

机构：

[1] HOKKAIDO UNIV,FAC PHARMACEUT SCI,KITA KU,SAPPORO,HOKKAIDO 060,JAPAN

[2] UNIV OCCUPAT & ENVIRONM HLTH,INST IND ECOL SCI,DEPT ENVIRONM ONCOL,YAHATANISHI KU,KITAKYUSHU,FUKUOKA 807,JAPAN

来源：

CHEMICAL COMMUNICATIONS | 1996年 / 02期

关键词：

D O I：

10.1039/cc9960000265

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Permanganate oxidation of 7,8-dihydro-8-oxoguanine in DNA oligomers causes damage to the neighbouring nucleotide residues; a highly reactive residue is the guanine next to the 8-oxoguanine.

引用

页码：265 / 266

页数：2

共 17 条

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