Multi-responsive hydrogels based on N-isopropylacrylamide and sodium alginate

被引：81

作者：

Dumitriu, Raluca P. ^{[1
]}

Mitchell, Geoffrey R. ^{[2
,3
]}

Vasile, Cornelia ^{[1
]}

机构：

[1] Petru Poni Inst Macromol Chem, Phys Chem Polymers Dept, Iasi 700487, Romania

[2] Univ Reading, Ctr Adv Microscopy, Reading RG6 6AF, Berks, England

[3] Univ Reading, Ctr Polymer Sci, Reading RG6 6AF, Berks, England

来源：

POLYMER INTERNATIONAL | 2011年 / 60卷 / 02期

关键词：

hydrogels; alginate; N-isopropylacrylamide; stimuli-responsive; swelling; HYALURONIC-ACID HYDROGELS; DRUG-DELIVERY; IONIC-STRENGTH; ORAL DELIVERY; PROTEIN DRUGS; IPN HYDROGELS; POLYMER GEL; SEMI-IPN; PH; RELEASE;

D O I：

10.1002/pi.2929

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 [高分子化学与物理];

摘要：

Hydrogels consisting of sodium alginate and N-isopropylacrylamide covalently crosslinked with N,N'-methylenebisacrylamide were prepared. The mixed-interpenetrated networks obtained were characterized using elemental analysis, Fourier transform infrared and Raman spectroscopy, swelling measurements and environmental scanning electron microscopy. The thermo- and pH-responsive properties of these hydrogels were evidenced by their swelling behaviour, which depended also on the amount of crosslinking agent and hydrogel composition. (C) 2010 Society of Chemical Industry

引用

页码：222 / 233

页数：12

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