Polarity-specific transcranial direct current stimulation effects on object-selective neural responses in the inferior parietal lobe

被引：16

作者：

Almeida, Jorge ^{[1
,2
]}

Martins, Ana R. ^{[1
,2
]}

Bergstrom, Fredrik ^{[1
,2
]}

Amaral, Lenia ^{[1
,2
]}

Freixo, Andreia ^{[1
,2
]}

Ganho-Auila, Ana ^{[1
,2
]}

Kristensen, Stephanie ^{[1
,2
]}

Lee, Dongha ^{[1
,2
]}

Nogueira, Joana ^{[1
,2
]}

Ruttorf, Michaela ^{[3
]}

机构：

[1] Univ Coimbra, Proact Lab, Fac Psychol & Educ Sci, Coimbra, Portugal

[2] Univ Coimbra, Fac Psychol & Educ Sci, Coimbra, Portugal

[3] Heidelberg Univ, Med Fac Mannheim, Comp Assisted Clin Med, Heidelberg, Germany

来源：

CORTEX | 2017年 / 94卷

关键词：

tDCS; fMRI; Neuromodulation; IPL; Tools; TUNING REVEALS INTERACTIONS; MEP AMPLITUDE-MODULATION; HEALTHY-HUMAN SUBJECTS; SPATIAL-FREQUENCY; TDCS; DORSAL; KNOWLEDGE; CORTEX;

D O I：

10.1016/j.cortex.2017.07.001

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

010107 [宗教学]; 030301 [社会学]; 070906 [古生物学及地层学（含古人类学）];

摘要：

Neuromodulation techniques such as transcranial direct current stimulation (tDCS) are routinely used for treating neurological and neuropsychiatric disorders, and for enhancement of cognitive abilities. Recently, their effectiveness in modulating behavioral and neural responses has been questioned. Here we use excitatory and inhibitory tDCS prior to a functional magnetic resonance imaging (fMRI) experiment to show that neural responses for an area's preferred stimuli depend on the polarity of stimulation. This is an important, yet overlooked, data point in demonstrating the effectiveness of these stimulation techniques. Our results show that response preferences in the target area are dependent on the polarity of the tDCS session preceding the fMRI experiment these preferences are less distinct in the cathodal than in the anodal session. As such, we show unequivocally that tDCS modulates neural responses. This result is of the utmost importance in demonstrating the effectiveness of tDCS for clinical and experimental purposes. (C) 2017 Elsevier Ltd. All rights reserved.

引用

页码：176 / 181

页数：6

共 40 条

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