Blood pressure management in acute intracerebral haemorrhage guidelines are poorly implemented in clinical practice

被引:8
作者
Manawadu, Dulka [1 ]
Jeerakathil, Thomas
Roy, Amrita
Orwaard-Wong, Kim
Butcher, Ken [2 ]
机构
[1] Kings Coll Hosp NHS Fdn Trust, Dept Stroke Med, London, England
[2] Univ Alberta, Div Neurol, WMC Hlth Sci Ctr 2E3, Dept Med, Edmonton, AB T6G 2B7, Canada
关键词
Antihypertensive agents; Guidelines; Intracerebral haemorrhage; Hypertension; Outcome measures; HEMATOMA ENLARGEMENT; ARTERIAL-PRESSURE; STROKE COUNCIL; PREDICTORS; TRIAL; ASSOCIATION; GROWTH; CARE;
D O I
10.1016/j.clineuro.2010.07.009
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Background Optimal management of blood pressure (BP) in spontaneous intracerebral haemorrhage (ICH) is controversial We assessed adherence to BP guidelines and its management in ICH in a tertiary Canadian Stroke Centre Methods We conducted a retrospective analysis of 142 CT confirmed primary ICH patients admitted within 24 h of symptoms between 2005 and 2006 Initial practice with respect to BP control was reviewed and compared with current guidelines This retrospective sample was compared with a prospective cohort participating in a BP lowering trial for the attainment of pre-defined BP targets We also assessed the effect of BP treatment on hematoma expansion and mortality Results Blood pressure treatment orders were established in 73% of the 142 patients (median age 71 years, 61% male) Only 26% of patients had target orders as advised in the current ANA guidelines Only 54% achieved BP targets as compared with 83% of the prospective cohort within 1 h Patients with established BP orders were more likely to have repeat brain imaging (70 2%) than those without (39 5%, p 0 001 Mortality rates were 298% and 474% in those with and without BP targets respectively (p = 0 051) Conclusions Management of BP varies considerably and there appears to be little adherence to recommended guidelines Targets are achieved more rapidly if a BP treatment protocol is utilized (C) 2010 Published by Elsevier B V
引用
收藏
页码:858 / 864
页数:7
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