Pre- and postinvasion defenses both contribute to nonhost resistance in Arabidopsis

被引：589

作者：

Lipka, V

Dittgen, J

Bednarek, P

Bhat, R

Wiermer, M

Stein, M

Landtag, J

Brandt, W

Rosahl, S

Scheel, D

Llorente, F

Molina, A

Parker, J

Somerville, S

Schulze-Lefert, P

机构：

[1] Max Planck Inst Plant Breeding Res, Dept Plant Microbe Interact, D-50829 Cologne, Germany

[2] Carnegie Inst Washington, Dept Plant Biol, Stanford, CA 94305 USA

[3] Inst Plant Biochem, Dept Stress & Dev Biol, D-06120 Halle Saale, Germany

[4] Inst Plant Biochem, Dept Bioorgan Chem, D-06120 Halle Saale, Germany

[5] Univ Politecn Madrid, Escuela Tecn Super Ingn Agron, Dept Biotecnol, Lab Bioquim & Biol Mol, E-28040 Madrid, Spain

来源：

SCIENCE | 2005年 / 310卷 / 5751期

关键词：

D O I：

10.1126/science.1119409

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Nonhost resistance describes the immunity of an entire plant species against nonadapted pathogen species. We report that Arabidopsis PEN2 restricts pathogen entry of two ascomycete powdery mildew fungi that in nature colonize grass and pea species. The PEN2 glycosyl hydrolase localizes to peroxisomes and acts as a component of an inducible preinvasion resistance mechanism. Postinvasion fungal growth is blocked by a separate resistance layer requiring the EDS1-PAD4-SAG101 signaling complex, which is known to function in basal and resistance (R) gene-triggered immunity. Concurrent impairment of pre- and postinvasion resistance renders Arabidopsis a host for both nonadapted fungi.

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页码：1180 / 1183

页数：4

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