Novel labdane diterpenes from the insecticidal plant Hyptis spicigera

被引：25

作者：

Fragoso-Serrano, M ^{[1
]}

González-Chimeo, E ^{[1
]}

Pereda-Miranda, R ^{[1
]}

机构：

[1] Univ Nacl Autonoma Mexico, Fac Quim, Dept Farm, Coyoacan 04510, DF, Mexico

来源：

JOURNAL OF NATURAL PRODUCTS | 1999年 / 62卷 / 01期

关键词：

D O I：

10.1021/np980222z

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Seven new labdane diterpenes with insecticidal properties were isolated from the aerial parts of Hyptis spicigera. Their structures were established on the basis of spectral (MS, H-1 NMR, and C-13 NMR) and chemical evidences as:19-acetoxy-2 alpha,7 alpha,15-trihydroxylabda-8(17),(13Z)-diene(1); 15,19-diacetoxy-2 alpha,7 alpha-dihydroxylabda-8(17),(13Z)-diene (2); 7 alpha,15, 19-triacetoxy-2 alpha-hydroxylabda-8(17),(13Z)-diene (3); 19-acetoxy-2 alpha,7 alpha-dihydroxylabda-8(17),(13Z)-dien-15-al (4); 19-acetoxy-2 alpha,7 alpha-dihydroxylabda-8(17),(13Z)-dien-2-one (5); 19-acetoxy-2 alpha,7 alpha-dihydroxylabda- 14,15-dinorlabd-8(17)-en-13-one (6); and 2 alpha,7 alpha,15,19-tetrahydroxy-ent-labda-8(17),(13Z)-diene (7). Absolute configurations were established by application of Mosher's method. Compound 2 significantly inhibited larval growth of the European corn borer.

引用

页码：45 / 50

页数：6

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