Mild oxidative one-pot allyl group cleavage

被引：38

作者：

Kitov, PI ^{[1
]}

Bundle, DR ^{[1
]}

机构：

[1] Univ Alberta, Dept Chem, Edmonton, AB T6G 2G2, Canada

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 18期

关键词：

D O I：

10.1021/ol016278t

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A new one-pot method is described for the removal of O- and N-allyl protecting groups under oxidative conditions at near neutral pH. The allyl group undergoes hydroxylation and subsequent periodate scission of the vicinal diol, followed by repetition of this reaction sequence on the enolic form of the aldehyde intermediate.

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页码：2835 / 2838

页数：4

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