Influence of anthocyanosides on human connective tissue metabolism

被引:9
作者
Boniface, R [1 ]
Robert, AM [1 ]
机构
[1] UNIV PARIS 12,FAK MED,LAB BINDEGEWEBSBIOCHEM,F-94010 CRETEIL,FRANCE
关键词
anthocyanosides; diabetic retinopathy; blindness; collagen; mucopolysaccharide; radiolabeled aminoacids; Vaccinium myrtillus; L;
D O I
10.1055/s-2008-1035336
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Background Diabetic retinopathy can lead to blindness. This is due to an abnormally increased synthesis of connective tissue in order to a) repair leaking capillaries and b) formation of new capillaries. Method Twelve adult diabetics were treated with 600 mg anthocyanosides per day for two months. Samples of gingiva tissue were taken before and after treatment. Incubated with radio-active labeled aminoacids, the measure of radioactivity from different connective tissue extracts can show a changed protein biosynthesis activity. Results The use of radio-active labeled aminoacids show significant decrease of biosynthesis-activity of connective tissue especially polymeric collagene and structure-glycoproteins by anthocyanoside medication. Conclusions Anthocyanosides help to prevent diabetics from injuries caused by malfunction of synthesis-activities throughout normal diabetic medical treatment.
引用
收藏
页码:368 / 372
页数:5
相关论文
共 10 条
[1]  
CAMERINIDAVALOS RA, 1979, FRONTIERS MATRIX BIO, V7, P281
[2]  
Huismans H, 1988, AUGENSPIEGEL, V34, P16
[3]  
LAGRUE G, 1979, FRONT MATRIX BIOL, V7, P324
[4]  
MISKULIN M, 1979, THESIS U PARIS 7
[5]  
REPOSSI P, 1987, ANN OFTALMOL CLIN OC, V4, P357
[6]  
ROBERT AM, 1977, J MED, V8, P321
[7]  
ROBERT AM, 1979, FRONT MATRIX BIOL, V7, P314
[8]  
ROBERT L, 1970, J DIABETOL HOT DIEU, P203
[9]  
ROMANI JD, 1974, MED PRATICIENNE
[10]  
ROMANI JD, 1969, CR S INT PAR VASC FL, P94