Gold-catalyzed cyclization of (Z)-2-en-4-yn-1-ols:: Highly efficient synthesis of fully substituted dihydrofurans and furans

被引：260

作者：

Liu, YH

Song, FJ

Song, ZQ

Liu, MN

Yan, B

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organomet Chem, Shanghai 200032, Peoples R China

[2] Hebei Normal Univ, Coll Chem & Mat Sci, Shijiazhuang 050091, Hebei, Peoples R China

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 24期

关键词：

D O I：

10.1021/ol052160r

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The gold-catalyzed cyclization of (Z)-enynois offers an efficient and straightforward route to stereodefined (Z)-5-ylidene-2,5-dihydrofurans and fully substituted furans under extremely mild reaction conditions. Importantly, the results indicated that both the oxyauration and the protodemetalation steps are highly stereoselective.

引用

页码：5409 / 5412

页数：4

共 48 条

[1]

[Anonymous], 2003, CHEM HETEROCYCLES ST, DOI DOI 10.1002/352760183X

[2] THE PALLADIUM-CATALYZED SYNTHESIS OF 2,3,5-TRISUBSTITUTED FURANS FROM 2-PROPARGYL-1,3-DICARBONYL COMPOUNDS AND VINYLIC OR ARYL TRIFLATES OR HALIDES [J].