Reactivation of Epstein-Barr virus in patients with systemic lupus erythematosus

被引：40

作者：

Huggins, ML ^{[1
]}

Todd, I ^{[1
]}

Powell, RJ ^{[1
]}

机构：

[1] Univ Nottingham, Queens Med Ctr, Sch Mol Med Sci, Div Immunol, Nottingham NG7 2UH, England

来源：

RHEUMATOLOGY INTERNATIONAL | 2005年 / 25卷 / 03期

关键词：

antibodies; Epstein-Barr virus; reactivation; systemic lupus erythematosus;

D O I：

10.1007/s00296-003-0420-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A link between Epstein-Barr Virus (EBV) and systemic lupus erythematosus (SLE) has been suggested. However, recent advances in molecular technology now permit more detailed analysis. Sera from SLE patients were tested for antibodies to several EBV antigens and had a significantly higher prevalence of immunoglobulin G antibodies against EBV early antigens than in normal or disease controls. This suggests that recent EBV infection or virus reactivation was occurring in these patients.

引用

页码：183 / 187

页数：5

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