(Coumarin-4-yl)methyl esters as highly efficient, ultrafast phototriggers for protons and their application to acidifying membrane surfaces

被引：79

作者：

Geissler, D

Antonenko, YN

Schmidt, R

Keller, S

Krylova, OO

Wiesner, B

Bendig, J

Pohl, P

Hagen, V

机构：

[1] Forschungsinst Mol Pharmakol, D-13125 Berlin, Germany

[2] Moscow MV Lomonosov State Univ, AN Belozersky Inst Physicochem Biol, Moscow, Russia

[3] Univ Frankfurt, Inst Phys & Theoret Chem, D-6000 Frankfurt, Germany

[4] Humboldt Univ, Inst Chem, Berlin, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 08期

关键词：

membranes; photoactivatable compounds; photolysis; protecting groups; protons;

D O I：

10.1002/anie.200461567

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Large jumps in pH on the nanosecond timescale can be achieved upon one- and two-photon flash photolysis of novel coumarinylmethyl esters, which are phototriggers for H+ (see scheme, F = pH-sensitive fluorescence indicator). The compounds are excellent tools for the study of rapid H +-triggered processes, for example, proton migration along membrane surfaces. © 2005 Wiley-VCH Verlag GmbH & Co. KCaA, Weinheim.

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页码：1195 / 1198

页数：4

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