Bioactive constituents of Leptadenia arborea

被引：43

作者：

El-Hassan, A

El-Sayed, M

Hamed, AI

Rhee, IK

Ahmed, AA

Zeller, KP

Verpoorte, R ^{[1
]}

机构：

[1] Leiden Univ, LACDR, Div Pharmacognosy, NL-2300 RA Leiden, Netherlands

[2] Menia Univ, Fac Sci, Dept Chem, Menia 61519, Egypt

[3] S Valley Univ, Fac Sci, Aswan, Egypt

[4] Univ Tubingen, Inst Organ Chem, D-72076 Tubingen, Germany

来源：

FITOTERAPIA | 2003年 / 74卷 / 1-2期

关键词：

Leptadenia arborea; pinoresinol; syringaresinal; leucanthemitol; E-ferulaldehyde; NMR; MS;

D O I：

10.1016/S0367-326X(02)00314-3

中图分类号：

R914 [药物化学];

学科分类号：

100701 [药物化学];

摘要：

The aerial part of Leptadenia arborea has been shown to contain pinoresinol (1), syringaresinol (2), leucanthemitol (3) and E-ferulaldehyde (4). These known compounds are being reported for the first time from this plant. Among them, syringaresinol has shown an inhibitory effect against acetylcholinesterase. The IC50 (the concentration of 50% enzyme inhibition) value of this compound was 200 mug/ml. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：184 / 187

页数：4

共 6 条

[1]

El-Moghazy A. M., 1980, Fitoterapia, V51, P321

[2]

KRISHNA GVP, 1975, PLANTA MED, V27, P395

[3]

Narasimhamurthy G, 1969, Indian Vet J, V46, P510

[4]

Triterpenoids from Leptadenia hastata latex [J].