HiDden targets of microRNAs for growth control

被引：26

作者：

Bergmann, A

Lane, ME

机构：

[1] Univ Texas, MD Anderson Canc Ctr, Dept Biochem & Mol Biol, Houston, TX 77030 USA

[2] Rice Univ, Dept Biochem & Cell Biol, Houston, TX 77005 USA

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 2003年 / 28卷 / 09期

关键词：

D O I：

10.1016/S0968-0004(03)00175-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

How is the size of an animal determined? Why is it that humans grow larger than mice? Certainly, one of the most astonishing features of animal development is that every animal of a given species, and its organs and appendages, grow to approximately the same size. Surprisingly little is known about the biology of tissue growth and size control. Recent advances in Drosophila research have implicated a microRNA as an important regulator of animal size. These studies reveal an unexpected layer of size regulation in higher animals.

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页码：461 / 463

页数：3

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