An increasingly complex view of intestinal motility

被引：30

作者：

Rao, Meenakshi ^{[1
,2
]}

机构：

[1] Boston Children's Hosp Boston, Div Gastroenterol, Hepatol, Nutr, Boston, MA USA

[2] Harvard Med Sch, Dept Pediat, Boston, MA USA

来源：

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY | 2020年 / 17卷 / 02期

关键词：

D O I：

10.1038/s41575-019-0249-0

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

Key advances Regional differences in colonic motor patterns might emerge from regional differences in the composition of enteric ganglia and the connectivity of component neurons.4 Extrinsic spinal afferent neurons that innervate the gut modulate the activity of myenteric neurons and stimulate gut contractions via a parasympathetic spinal circuit.5 The probiotic Lactobacillus rhamnosus GG alters enteric nervous system function and accelerates gut transit in an adhesion-dependent and redox-dependent manner.9 Key studies published in 2019 shed new light on how complex motor patterns emerge from the functional organization of circuits in the enteric nervous system and, in turn, how extrinsic afferent neurons and common commensal microorganisms interface with these circuits to modulate intestinal motility.

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收藏

页码：72 / 73

页数：2

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