Reproductive factors and risk of uterine fibroids

被引:108
作者
Parazzini, F
Negri, E
LaVecchia, C
Chatenoud, L
Ricci, E
Guarnerio, P
机构
[1] Ist. Ric. Farmacologiche Mario Negri, Milan
[2] Ist. di Stat. Medica e Biometria, Università di Milano, Milan
[3] Ist. Ric. Farmacologiche Mario Negri, 20157 Milan
关键词
uterine leiomyomas; reproductive factors; risk factors;
D O I
10.1097/00001648-199607000-00018
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
We analyzed the relation between reproductive history and risk of uterine fibroids using data from a case-control study. Cases were 621 women with histologically confirmed diagnosis of uterine fibroids. Controls were 1,051 nonhysterectomized patients. Compared with nulliparae, parous women had a relative risk (RR) of fibroids of 0.5 [95% confidence interval (CI) = 0.4-0.6], and the risk declined with number of births. The risk of fibroids also decreased with number of induced abortions (RR = 0.8 and 0.6 for women reporting one or two or more abortions, respectively). A total of 24 cases (3.9%) and 19 controls (1.8%) reported a history of infertility (RR = 2.0; 95% Cl = 1.1-3.7).
引用
收藏
页码:440 / 442
页数:3
相关论文
共 9 条
  • [1] [Anonymous], J AM STAT ASSOC
  • [2] BAKER RJ, 1978, GLIM SYSTEM
  • [3] BUTTRAM VC, 1981, FERTIL STERIL, V36, P433
  • [4] MANTEL N, 1959, J NATL CANCER I, V22, P719
  • [5] MOORE JG, 1986, GYNECOL OBSTET, V1, P5
  • [6] ORAL-CONTRACEPTIVE USE AND RISK OF UTERINE FIBROIDS
    PARAZZINI, F
    NEGRI, E
    LAVECCHIA, C
    FEDELE, L
    RABAIOTTI, M
    LUCHINI, L
    [J]. OBSTETRICS AND GYNECOLOGY, 1992, 79 (03) : 430 - 433
  • [7] EPIDEMIOLOGIC CHARACTERISTICS OF WOMEN WITH UTERINE FIBROIDS - A CASE-CONTROL STUDY
    PARAZZINI, F
    LAVECCHIA, C
    NEGRI, E
    CECCHETTI, G
    FEDELE, L
    [J]. OBSTETRICS AND GYNECOLOGY, 1988, 72 (06) : 853 - 857
  • [8] PARAZZINI F, 1993, REV EPIDEMIOL SANTE, V41, P480
  • [9] RISK-FACTORS FOR UTERINE FIBROIDS - REDUCED RISK ASSOCIATED WITH ORAL-CONTRACEPTIVES
    ROSS, RK
    PIKE, MC
    VESSEY, MP
    BULL, D
    YEATES, D
    CASAGRANDE, JT
    [J]. BRITISH MEDICAL JOURNAL, 1986, 293 (6543) : 359 - 362