Controlling influences in bisspiroketal formation: synthesis of the ABC ring system of azaspiracid

被引：19

作者：

Carter, RG ^{[1
]}

Bourland, TC ^{[1
]}

Zhou, XT ^{[1
]}

Gronemeyer, MA ^{[1
]}

机构：

[1] Oregon State Univ, Dept Chem, Corvallis, OR 97331 USA

来源：

TETRAHEDRON | 2003年 / 59卷 / 45期

基金：

美国国家卫生研究院;

关键词：

azaspiracid; bisspiroketal; bisspirocyclization; Julia coupling; substituent effects; anomeric effect;

D O I：

10.1016/j.tet.2003.03.003

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Substitution effects on the stereochemical outcome of bisspiroketalization on the C-1-C-17 carbon backbone of azaspiracid is presented. A possible explanation is offered to explain the observed stereochemical outcome. (C) 2003 Elsevier Ltd. All rights reserved.

引用

收藏

页码：8963 / 8974

页数：12

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