A global perspective on the epidemiology of West Nile virus
被引:374
作者:
Kramer, Laura D.
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机构:
Wadsworth Ctr, New York State Dept Hlth, Arbovirus Labs, New York, NY 12159 USA
SUNY Albany, Sch Publ Hlth, Dept Biomed Sci, Albany, NY 12201 USAWadsworth Ctr, New York State Dept Hlth, Arbovirus Labs, New York, NY 12159 USA
Kramer, Laura D.
[1
,2
]
Styer, Linda M.
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机构:
Wadsworth Ctr, New York State Dept Hlth, Arbovirus Labs, New York, NY 12159 USAWadsworth Ctr, New York State Dept Hlth, Arbovirus Labs, New York, NY 12159 USA
Styer, Linda M.
[1
]
Ebel, Gregory D.
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机构:
Univ New Mexico, Sch Med, Dept Pathol, Albuquerque, NM 87131 USAWadsworth Ctr, New York State Dept Hlth, Arbovirus Labs, New York, NY 12159 USA
Ebel, Gregory D.
[3
]
机构:
[1] Wadsworth Ctr, New York State Dept Hlth, Arbovirus Labs, New York, NY 12159 USA
[2] SUNY Albany, Sch Publ Hlth, Dept Biomed Sci, Albany, NY 12201 USA
[3] Univ New Mexico, Sch Med, Dept Pathol, Albuquerque, NM 87131 USA
West Nile virus (WNV) (Flavivirus: Flaviviridae) is the most widespread arbovirus in the world. A significant range expansion occurred beginning in 1999 when the virus was introduced into New York City. This review highlights recent research into WNV epizootiology and epidemiology, including recent advances in understanding of the host-virus interaction at the molecular, organismal, and ecological levels. Vector control strategies, vaccines, and antivirals, which now must be considered on a global scale, are also discussed.