Gene-altered islets for transplant: Giant leap or small step?

[1] Pharmacological treatment of chronic diabetes by stimulating pancreatic β-cell regeneration with systemic co-administration of EGF and gastrin [J]. PHARMACOLOGY & TOXICOLOGY, 2002, 91 (06): : 414 - 420

[2] Portal venous pressure changes after sequential clinical islet transplantation [J]. TRANSPLANTATION, 2002, 74 (07) : 913 - 915

[3] Overexpression of parathyroid hormone-related protein inhibits pancreatic β-cell death in vivo and in vitro [J]. DIABETES, 2002, 51 (10) : 3003 - 3013

[4] Role of endogenous glucagon-like peptide-1 in islet regeneration after partial pancreatectomy [J]. DIABETES, 2003, 52 (02) : 365 - 371

[5] Glucagon-like peptide 1 inhibits cell apoptosis and improves glucose responsiveness of freshly isolated human islets [J]. ENDOCRINOLOGY, 2003, 144 (12) : 5149 - 5158

[6] Gaglia JL, 2001, CURR DIRECT AUTOIMMU, V4, P283

[7] Adenovirus-mediated hepatocyte growth factor expression in mouse islets improves pancreatic islet transplant performance and reduces beta cell death [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (01) : 343 - 351

[8] Transgenic overexpression of hepatocyte growth factor in the β-cell markedly improves islet function and islet transplant outcomes in mice [J]. DIABETES, 2001, 50 (12) : 2752 - 2762

[9] Hepatocyte growth factor overexpression in the islet of transgenic mice increases beta cell proliferation, enhances islet mass, and induces mild hypoglycemia [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (02) : 1226 - 1232

[10] Gelsinger Paul, 2002, Bull Med Ethics, P13

[1] Pharmacological treatment of chronic diabetes by stimulating pancreatic β-cell regeneration with systemic co-administration of EGF and gastrin [J]. PHARMACOLOGY & TOXICOLOGY, 2002, 91 (06): : 414 - 420

[2] Portal venous pressure changes after sequential clinical islet transplantation [J]. TRANSPLANTATION, 2002, 74 (07) : 913 - 915

[3] Overexpression of parathyroid hormone-related protein inhibits pancreatic β-cell death in vivo and in vitro [J]. DIABETES, 2002, 51 (10) : 3003 - 3013

[4] Role of endogenous glucagon-like peptide-1 in islet regeneration after partial pancreatectomy [J]. DIABETES, 2003, 52 (02) : 365 - 371

[5] Glucagon-like peptide 1 inhibits cell apoptosis and improves glucose responsiveness of freshly isolated human islets [J]. ENDOCRINOLOGY, 2003, 144 (12) : 5149 - 5158

[6] Gaglia JL, 2001, CURR DIRECT AUTOIMMU, V4, P283

[7] Adenovirus-mediated hepatocyte growth factor expression in mouse islets improves pancreatic islet transplant performance and reduces beta cell death [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (01) : 343 - 351

[8] Transgenic overexpression of hepatocyte growth factor in the β-cell markedly improves islet function and islet transplant outcomes in mice [J]. DIABETES, 2001, 50 (12) : 2752 - 2762

[9] Hepatocyte growth factor overexpression in the islet of transgenic mice increases beta cell proliferation, enhances islet mass, and induces mild hypoglycemia [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (02) : 1226 - 1232

[10] Gelsinger Paul, 2002, Bull Med Ethics, P13