Risk Factors for Incident Condyloma in a Multinational Cohort of Men: The HIM Study

被引：26

作者：

Anic, Gabriella M. ^{[2
]}

Lee, Ji-Hyun

Villa, Luisa L. ^{[3
]}

Lazcano-Ponce, Eduardo ^{[4
]}

Gage, Christine

Silva, Roberto Jose C. ^{[5
]}

Baggio, Maria L. ^{[3
]}

Quiterio, Manuel ^{[4
,6
]}

Salmeron, Jorge ^{[4
,6
]}

Papenfuss, Mary R.

Abrahamsen, Martha

Stockwell, Heather ^{[2
]}

Rollison, Dana E.

Wu, Yougui ^{[2
]}

Giuliano, Anna R. ^{[1
]}

机构：

[1] H Lee Moffitt Canc Ctr & Res Inst, MRC CANCONT, Dept Canc Epidemiol, Tampa, FL 33612 USA

[2] Univ S Florida, Coll Publ Hlth, Dept Epidemiol & Biostat, Tampa, FL USA

[3] Ludwig Inst Canc Res, Sao Paulo, Brazil

[4] Inst Nacl Salud Publ, Cuernavaca, Morelos, Mexico

[5] Ctr Referencia DST Aids, Sao Paulo, Brazil

[6] Inst Mexicano Seguro Social, Cuernavaca, Morelos, Mexico

来源：

JOURNAL OF INFECTIOUS DISEASES | 2012年 / 205卷 / 05期

基金：

美国国家卫生研究院;

关键词：

PAPILLOMAVIRUS TYPES 6; GENITAL WARTS; UNITED-STATES; NATURAL-HISTORY; HEALTH;

D O I：

10.1093/infdis/jir851

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Identifying factors associated with condyloma are necessary for prevention efforts. Risk factors for incident condyloma were examined in a cohort of 2487 men from the United States, Brazil, and Mexico and were followed up every 6 months (median, 17.9 months). Factors strongly associated with condyloma were incident infection with human papillomavirus (HPV) types 6 and 11 (hazard ratio [HR], 12.42 [95% confidence interval {CI}, 3.78-40.77]), age (HR, 0.43 [95% CI, .26-.77]; 45-70 vs 18-30 years), high lifetime number of female partners (HR, 5.69 [95% CI, 1.80-17.97]; >= 21 vs 0 partners), and number of male partners (HR, 4.53 [95% CI, 1.68-12.20]; >= 3 vs 0 partners). The results suggest that HPV types 6 and 11 and recent sexual behavior are strongly associated with incident condyloma.

引用

页码：789 / 793

页数：5

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