Cytotoxic oxygenated desmosterols of the red alga Galaxaura marginata

被引：56

作者：

Sheu, JH

Huang, SY

Duh, CY

机构：

[1] Department of Marine Resources, National Sun Yat-Sen University

来源：

JOURNAL OF NATURAL PRODUCTS | 1996年 / 59卷 / 01期

关键词：

D O I：

10.1021/np960016w

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Desmosterol (1), 24,25-epoxycholesterol (2), 24-hydroperoxycholesta-5,25-dien-3 beta-ol (3), 25-hydroperoxycholesta-5,23(E)-dien-3 beta-ol (4), cholesta-5,25-diene-3 beta,24-diol (5), and 24,25-epoxy-6 beta-hydroxycholest-4-en-3-one (7) were isolated from the marine red alga Galaxaura marginata; sterols 3, 4, and 7 were isolated for the first time from a natural source. Sterols 3-7 exhibited significant cytotoxicity toward serveral cancer cell lines.

引用

页码：23 / 26

页数：4

共 20 条

[1]

[Anonymous], 1994, NAT PROD LETT, DOI 10.1080/10575639408043928

[2] ENE REACTIONS OF ALLYLICALLY STANNYLATED CHOLESTENES - SINGLET OXYGENATION OF 7-ALPHA-TRIPHENYLSTANNYLCHOLEST-5-EN-3-BETA-OL, AND OF 7-ALPHA-TRIPHENYLSTANNYL-CHOLEST-5-ENE-3-ONE AND 7-ALPHA-TRIBUTYLSTANNYL-CHOLEST-5-ENE-3-ONE, AND THE REARRANGEMENT OF 5-ALPHA-TRIBUTYLSTANNYLPEROXY-3-BETA-BENZOYLOXYCHOLEST-6-ENE AND OF 7-ALPHA-TRIBUTYLSTANNYLPEROXY-3-BETA-BENZOYLOXYCHOLEST-5-ENE [J].