Disintegration of Staphylococcus epidermidis biofilms under glucose-limiting conditions depends on the activity of the alternative sigma factor σB

被引：28

作者：

Jäger, S

Mack, D

Rohde, H

Horstkotte, MA

Knobloch, JKM

机构：

[1] Univ Hamburg, Klinikum Eppendorf, Zentrum Klin Theoret Med 1, Inst Infekt Med, D-20246 Hamburg, Germany

[2] Univ Coll Swansea, Sch Med, Dept Med Microbiol & Infect Dis, Swansea SA2 8PP, W Glam, Wales

来源：

APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 2005年 / 71卷 / 09期

关键词：

D O I：

10.1128/AEM.71.9.5577-5581.2005

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

To evaluate the role of the polysaccharide intercellular adhesin as an energy-storage molecule, we investigated the effect of nutrient limitation on S. epidermidis biofilms. The stability of established biofilms depends on sigma(B) activity; however, the slow decay of biofilms under conditions of nutrient limitation reveal its use as an energy-storage molecule to be unlikely.

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页码：5577 / 5581

页数：5

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