Five unique compounds:: Xyloketals from mangrove fungus Xylaria sp from the South China Sea coast

被引：275

作者：

Lin, YC ^{[1
]}

Wu, XY

Feng, SA

Jiang, GC

Luo, JH

Zhou, SN

Vrijmoed, LLP

Jones, EBG

Krohn, K

Steingröver, K

Zsila, F

机构：

[1] Zhongshan Univ, Dept Appl Chem, Guangzhou, Peoples R China

[2] Inst Chem CRC, Dept Mol Pharmacol, H-1525 Budapest, Hungary

[3] Univ Gesamthsch Paderborn, Fachbereich Chem & Chem Tech, D-33098 Paderborn, Germany

[4] City Univ Hong Kong, Dept Biol & Chem, Hong Kong, Hong Kong, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2001年 / 66卷 / 19期

关键词：

D O I：

10.1021/jo015522r

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Five unique metabolites, xyloketals A (1), B (2), C (3), D (4), and E (5), and the known 6 were isolated from mangrove fungus Xylaria sp. (no. 2508), obtained from the South China Sea. The structures of these compounds were elucidated by spectroscopic and X-ray diffraction experiments. Xyloketal A is a ketal compound with a C-3 symmetry and xyloketals B-E are its analogues. It was found that xytoketal C slowly rearranged to xytoketal B in DMSO-d(6) Solution at room temperature. Xyloketal A exhibited the activity of inhibiting acetylcholine esterase.

引用

页码：6252 / 6256

页数：5

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