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On the origins of triterpenoid skeletal diversity

被引：456
作者：
Xu, R
Fazio, GC
Matsuda, SPT
机构：
[1] Rice Univ, Dept Chem, Houston, TX 77005 USA
[2] Rice Univ, Dept Biochem & Cell Biol, Houston, TX 77005 USA
来源：
PHYTOCHEMISTRY | 2004年 / 65卷 / 03期
关键词：
triterpene; triterpenoid; oxidosqualene cyclization; squalene; cyclization; isoprene rule;
D O I：
10.1016/j.phytochem.2003.11.014
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The triterpenoids are a large group of natural products derived from C-30 precursors. Nearly 200 different triterpene skeletons are known from natural sources or enzymatic reactions that are structurally consistent with being cyclization products of squalene, oxidosqualene, or, bis-oxidosqualene. This review categorizes each of these structures and provides mechanisms for their formation. (C) 2003 Elsevier Ltd. All rights reserved.
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收藏
页码：261 / 291
页数：31
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