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Epstein-Barr virus-associated peripheral T-cell lymphoma and hemophagocytic syndrome arising after liver transplantation: Case report and review of the literature

被引：36
作者：
George, TI
Jeng, M
Berquist, W
Cherry, AM
Link, MP
Arber, DA
机构：
[1] Stanford Univ, Sch Med, Ctr Med, Dept Pathol, Stanford, CA 94305 USA
[2] Stanford Univ, Sch Med, Dept Pediat, Stanford, CA 94305 USA
来源：
PEDIATRIC BLOOD & CANCER | 2005年 / 44卷 / 03期
关键词：
Epstein-Barr virus (EBV); hemophagocytic syndrome; peripheral T-cell lymphoma; post-transplant lymphoproliferative disorder (PTLD);
D O I：
10.1002/pbc.20231
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Post-transplantation lymphoproliferative disorders (PTLD) are a well-recognized complication of solid organ transplantation. The vast majority of PTLD are Epstein-Barr virus (EBV)-related infections that manifest as B-cell malignancies. We report an unusual case of an EBV-associated T-cell lymphoma in a 10-year-old boy who had previously undergone liver transplantation at age 4 years. He presented with hemophagocytic syndrome (HPS) and active EBV infection, with positive serum titers and polymerase chain reaction (PCR) for EBV in blood, colon, and antral samples. (C) 2004 Wiley-Liss, Inc.
引用
收藏
页码：270 / 276
页数：7
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