Taking the A-train: actin-based force generators and organelle targeting

被引：26

作者：

Fehrenbacher, KL ^{[1
]}

Boldogh, IR ^{[1
]}

Pon, LA ^{[1
]}

机构：

[1] Columbia Univ, Dept Anat & Cell Biol, New York, NY 10032 USA

来源：

TRENDS IN CELL BIOLOGY | 2003年 / 13卷 / 09期

关键词：

D O I：

10.1016/S0962-8924(03)00174-0

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The actin-driven process of cytoplasmic streaming in plant cells is widely believed to be the earliest documented example of cytoskeleton-driven organelle movement. In the decades since these seminal findings, two mechanisms of actin-based intracellular movement have been identified in multiple cell types: one is myosin dependent and the other is dependent upon the Arp2/3 complex for actin nucleation and polymerization. Here, we describe mechanisms of force generation and directed movement that use the actin cytoskeleton, as well as those that target actin-dependent force generators to different subcellular compartments.

引用

页码：472 / 477

页数：6

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