Synthesis of novel 1,2,5,6-tetrahydro-4H-pyrrolo [3,2,1-ij]-quinolines via benzotriazole methodology

被引：13

作者：

Abonia, R ^{[1
]}

Albornoz, A

Insuasty, B

Quiroga, J

Meier, H

Hormaza, A

Nogueras, M

Sánchez, A

Cobo, J

Low, JN

机构：

[1] Univ Valle, Dept Chem, Grp Invest Compuestos Heterocicl, Cali AA25360, Colombia

[2] Univ Mainz, Inst Organ Chem, D-55099 Mainz, Germany

[3] Univ Jaen, Dept Quim Inorgan & Organ, Jaen 23071, Spain

[4] Univ Aberdeen, Dept Chem, Old Aberdeen AB24 3UE, Scotland

来源：

TETRAHEDRON | 2001年 / 57卷 / 23期

关键词：

indolines; benzotriazole; alkenes; cyclization; 1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-if]quinolines; lilolidine;

D O I：

10.1016/S0040-4020(01)00436-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Pyrroloquinolines have been synthesized reacting 1-(benzotriazol-1(2)-ylmethyl)indolines with unactivated and electron-rich alkenes in the presence of p-toluenesulfonic acid catalyst. Mixtures of the expected diastereomers were obtained and some of them separated in their respective components. X-Ray diffraction along with two-dimensional NMR experiments was needed to assist the determination for both the structures of the precursors and products. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：4933 / 4938

页数：6

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