A reinvestigation of the preparation, properties, and applications of aminomethyl and 4-methylbenzhydrylamine polystyrene resins

被引：87

作者：

Adams, JH ^{[1
]}

Cook, RM ^{[1
]}

Hudson, D ^{[1
]}

Jammalamadaka, V ^{[1
]}

Lyttle, MH ^{[1
]}

Songster, MF ^{[1
]}

机构：

[1] Solid Phase Sci, Novato, CA 94949 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1998年 / 63卷 / 11期

关键词：

D O I：

10.1021/jo9802269

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Mild, efficient conditions have been developed for the preparation of 4-methylbenzhydrylamine polystyrene (MBHA) and aminomethyl polystyrene (AMPS) resins by a two-step procedure with synthons 1a and 1c. The products possess excellent swelling characteristics and acylate readily with linkers yielding useful derivatives, which retain good swelling and reactivity. Comparative studies with these resins, and their poly(ethylene glycol) (PEG) derivatives, yield insights into the role of spacer arm and environment effects in synthesis facilitation.

引用

页码：3706 / 3716

页数：11

共 48 条

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