Analysing genetic information with DNA arrays

被引：41

作者：

Case-Green, SC ^{[1
]}

Mir, KU ^{[1
]}

Pritchard, CE ^{[1
]}

Southern, EM ^{[1
]}

机构：

[1] Univ Oxford, Dept Biochem, Oxford OX1 3QU, England

来源：

CURRENT OPINION IN CHEMICAL BIOLOGY | 1998年 / 2卷 / 03期

关键词：

D O I：

10.1016/S1367-5931(98)80016-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The large amount of DNA sequence information produced in recent years has created a need for high-throughput methods in biology and genetics. These include sequencing, comparing gene sequences and genotyping. DNA arrays promise a highly parallel means for analysis of DNA that is fast and cost-effective, and offers scope for application to complex systems and processes. Recent years have seen continued transfer of technology from the microelectronics industry. Rapid application of the technology to genotyping, antisense oligonucleotide selection and gene expression analysis has illustrated the general power of this approach.

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页码：404 / 410

页数：7

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