The ansacarbamitocins: Polar ansamitocin derivatives

被引：24

作者：

Snipes, Carl E. ^{[1
]}

Duebelbeis, Dennis O. ^{[1
]}

Olson, Monica ^{[1
]}

Hahn, Donald R. ^{[1
]}

Dent, William H., III ^{[1
]}

Gilbert, Jeffrey R. ^{[1
]}

Werk, Todd L. ^{[1
]}

Davis, George E. ^{[1
]}

Lee-Lu, Rebecca ^{[1
]}

Graupner, Paul R. ^{[1
]}

机构：

[1] Dow Agrosci, Indianapolis, IN 46268 USA

来源：

JOURNAL OF NATURAL PRODUCTS | 2007年 / 70卷 / 10期

关键词：

D O I：

10.1021/np070275t

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The ansacarbamitocins are a new family of maytansinoids that are unusually substituted with a glucose subunit and two carbamate functional groups and exhibit modest activity against some agricultural fungal disease organisms. Ansacarbamitocins A-F (1-6) all consist of the same macrocyclic core as the ansamitocins, with variation occurring on the glucose unit, while ansacarbamitocins A1 and B1 (7, 8) additionally lack the epoxide group on C-4 and C-5.

引用

页码：1578 / 1581

页数：4

共 6 条

[1] ISOLATION, CHEMICAL CHARACTERIZATION AND STRUCTURE OF ANSAMITOCIN, A NEW ANTI-TUMOR ANSAMYCIN ANTIBIOTIC [J].