Chain-like assembly of gold nanoparticles on artificial DNA templates via 'click chemistry'

被引:106
作者
Fischler, Monika [1 ]
Sologubenko, Alla [2 ]
Mayer, Joachim [2 ]
Clever, Guido [3 ]
Burley, Glenn [3 ]
Gierlich, Johannes [3 ]
Carell, Thomas [3 ]
Simon, Ulrich [1 ]
机构
[1] Rhein Westfal TH Aachen, Inst Anorgan Chem, D-52074 Aachen, Germany
[2] Rhein Westfal TH Aachen, Gemeinschaftslabor Elektronenmikrosokopie, D-52074 Aachen, Germany
[3] LMU Munchen, Fak Chem & Pharm, D-81377 Munich, Germany
关键词
D O I
10.1039/b715602b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We present a new type of azide-functionalized gold nanoparticle and their coupling to an alkyne-modified DNA duplex using the copper(I)-catalyzed Huisgen cycloaddition ('click chemistry'), resulting in a chain-like assembly of nanoparticles on the DNA template.
引用
收藏
页码:169 / 171
页数:3
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