Antimicrobial and healing activity of kefir and kefiran extract

被引:249
作者
Rodrigues, KL
Caputo, LRG
Carvalho, JCT
Evangelista, J
Schneedorf, JM [1 ]
机构
[1] Univ Jose do Rosario Vellano, Lab Fitofarmacos, Alfenas, MG, Brazil
[2] Univ Jose do Rosario Vellano, Lab Patol Expt, Alfenas, MG, Brazil
[3] Univ Jose do Rosario Vellano, Lab Biol & Fisiol Microorganismos, Alfenas, MG, Brazil
关键词
kefir; kefiran; cicatrizing; antimicrobial;
D O I
10.1016/j.ijantimicag.2004.09.020
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Ketir and its insoluble polysaccharide, kefiran, were both tested for antimicrobial and cicatrizing activities against several bacterial species and Candida albicans using an agar diffusion method. Comparator antimicrobials were also tested. Cicatrizing experiments were carried out on Wistar rats with induced skin lesions and Staphylococcus aureus inoculation, using a topical application of a 70% kefir gel, Both ketir and kefiran showed some activity against all organisms tested, the highest activity was against streptococcus pyogenes, Cicatrizing experiments using 70% kefir gel had a protective effect on skin connective tissue and 7 days treatment enhanced wound healing compared with 5 mg/kg of neomycin-clostebol emulsion. (C) 2005 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.
引用
收藏
页码:404 / 408
页数:5
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