'Close-fitting sleeves': DNA damage recognition by the UvrABC nuclease system

被引:104
作者
Van Houten, B
Croteau, DL
DellaVecchia, MJ
Wang, H
Kisker, C
机构
[1] NIEHS, Mol Genet Lab, NIH, Res Triangle Pk, NC 27709 USA
[2] SUNY Stony Brook, Dept Pharmacol, Ctr Struct Biol, Stony Brook, NY 11794 USA
关键词
protein-DNA interaction; bacterial nucleotide excision repair; DNA damage recognition;
D O I
10.1016/j.mrfmmm.2005.03.013
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
DNA damage recognition represents a long-standing problem in the field of protein-DNA interactions. This article reviews our current knowledge of how damage recognition is achieved in bacterial nucleotide excision repair through the concerted action of the UvrA, UvrB, and UvrC proteins. Published by Elsevier B.V.
引用
收藏
页码:92 / 117
页数:26
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