Containment of an Outbreak of KPC-3-Producing Klebsiella pneumoniae in Italy

被引：74

作者：

Agodi, Antonella ^{[2
]}

Voulgari, Evangelia ^{[1
]}

Barchitta, Martina ^{[2
]}

Politi, Leda ^{[1
]}

Koumaki, Vasiliki ^{[1
]}

Spanakis, Nicholas ^{[1
]}

Giaquinta, Loredana ^{[3
]}

Valenti, Giovanna ^{[2
]}

Romeo, Maria Antonietta ^{[3
]}

Tsakris, Athanassios ^{[1
]}

机构：

[1] Univ Athens, Sch Med, Dept Microbiol, GR-11527 Athens, Greece

[2] Univ Catania, Dept GF Ingrassia, Catania, Italy

[3] Azienda Osped Cannizzaro, Catania, Italy

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2011年 / 49卷 / 11期

关键词：

CARBAPENEMASE; EMERGENCE; CLONE; PLASMID; KPC-2;

D O I：

10.1128/JCM.01242-11

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

From March 2009 to May 2009, 24 carbapenem-resistant Klebsiella pneumoniae isolates were recovered from 16 patients hospitalized in an Italian intensive care unit (ICU). All isolates contained KPC-3 carbapenemase and belonged to a single pulsed-field gel electrophoresis (PFGE) clone of multilocus sequence type 258 (designated as ST258). A multimodal infection control program was put into effect, and the spread of the KPC-3-producing K. pneumoniae clone was ultimately controlled without closing the ICU to new admissions. Reinforced infection control measures and strict monitoring of the staff adherence were necessary for the control of the outbreak.

引用

页码：3986 / 3989

页数：4

共 23 条

[1] Cross-transmission of Klebsiella pneumoniae in two intensive care units: intra- and inter-hospital spread [J].

Agodi, A. ;

Barchitta, M. ;

Valenti, G. ;

Romeo, M. A. ;

Giaquinta, L. ;

Santangelo, C. ;

Castiglione, G. ;

Tsakris, A. .

JOURNAL OF HOSPITAL INFECTION, 2011, 77 (03) :279-280

[2]

[Anonymous], J CLIN MICROBIOL

[3]

Babouee B, 2011, EUROSURVEILLANCE, V16, P16

[4] Antimicrobial Susceptibility Patterns of KPC-Producing or CTX-M-Producing Enterobacteriaceae [J].

Castanheira, Mariana ;

Sader, Helio S. ;

Jones, Ronald N. .

MICROBIAL DRUG RESISTANCE, 2010, 16 (01) :61-65

[5]

Clinical and Laboratory Standards Institute, 2010, CLSI M100S20

[6] Emergence of blaKPC-3-Tn4401a associated with a pKPN3/4-like plasmid within ST384 and ST388 Klebsiella pneumoniae clones in Spain [J].

Curiao, Tania ;

Isabel Morosini, Maria ;

Ruiz-Garbajosa, Patricia ;

Robustillo, Ana ;

Baquero, Fernando ;

Coque, Teresa M. ;

Canton, Rafael .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2010, 65 (08) :1608-1614

[7] Multilocus sequence typing of Klebsiella pneumoniae nosocomial isolates [J].

Diancourt, L ;

Passet, V ;

Verhoef, J ;

Grimont, PAD ;

Brisse, S .

JOURNAL OF CLINICAL MICROBIOLOGY, 2005, 43 (08) :4178-4182

[8] Characterization of blaKPC-containing Klebsiella pneumoniae isolates detected in different institutions in the Eastern USA [J].

Endimiani, Andrea ;

Hujer, Andrea M. ;

Perez, Federico ;

Bethel, Christopher R. ;

Hujer, Kristine M. ;

Kroeger, Jennifer ;

Oethinger, Margret ;

Paterson, David L. ;

Adams, Mark D. ;

Jacobs, Michael R. ;

Diekema, Daniel J. ;

Hall, Gerri S. ;

Jenkins, Stephen G. ;

Rice, Louis B. ;

Tenover, Fred C. ;

Bonomo, Robert A. .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2009, 63 (03) :427-437

[9] Emergence of KPC-producing Klebsiella pneumoniae in Italy [J].

Fontana C. ;

Favaro M. ;

Sarmati L. ;

Natoli S. ;

Altieri A. ;

Bossa M.C. ;

Minelli S. ;

Leonardis F. ;

Favalli C. .

BMC Research Notes, 3 (1)

[10] Emergence in Italy of Klebsiella pneumoniae Sequence Type 258 Producing KPC-3 Carbapenemase [J].

Giani, Tommaso ;

D'Andrea, Marco Maria ;

Pecile, Patrizia ;

Borgianni, Luisa ;

Nicoletti, Pierluigi ;

Tonelli, Francesco ;

Bartoloni, Alessandro ;

Rossolini, Gian Maria .

JOURNAL OF CLINICAL MICROBIOLOGY, 2009, 47 (11) :3793-3794

← 1 2 3 →