'Dormant' inhibitory neurons: do they exist and what is their functional impact?

被引：16

作者：

Jefferys, JGR ^{[1
]}

Traub, RD ^{[1
]}

机构：

[1] Univ Birmingham, Sch Med, Dept Physiol, Neurosci Unit, Birmingham B15 2TT, W Midlands, England

来源：

EPILEPSY RESEARCH | 1998年 / 32卷 / 1-2期

基金：

英国惠康基金;

关键词：

dormant interneurons; tetanus toxin model; chronic epilepsy;

D O I：

10.1016/S0920-1211(98)00044-8

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The concept of dormant interneurons is proving to be hard to define precisely. We argue here that the term is best used as an operational description of interneurons which are not lost from the epileptic brain, but which fail to perform adequately. We present evidence for the existence of functionally dormant interneurons in the tetanus toxin model of chronic epilepsy, and we explore the roles of a partial dormancy (and also of charge-screening) in the acute low magnesium model of epilepsy. (C) 1998 Elsevier Science B.V. All rights reserved.

引用

页码：104 / 113

页数：10

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