Efficient synthesis of the left-hand subunit of milbemycin beta 3 using a Suzuki coupling reaction.

被引:26
作者
Marko, IE [1 ]
Murphy, F [1 ]
Dolan, S [1 ]
机构
[1] GLAXO WELLCOME MED RES CTR,STEVENAGE SG1 2NY,HERTS,ENGLAND
关键词
D O I
10.1016/0040-4039(96)00305-X
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The efficient synthesis of the left-hand subunit of the antiparasitic agent milbemycin beta 3 using a Suzuki coupling is described. The unique role played by thallium carbonate in this palladium-catalysed reaction is discussed. Copyright (C) 1996 Elsevier Science Ltd.
引用
收藏
页码:2507 / 2510
页数:4
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