Who cares for a stressed brain? The mother, the kid or both?

被引：30

作者：

de Kloet, ER

Oitzl, MS

机构：

[1] Leiden Amsterdam Ctr Drug Res, Div Med Pharmacol, NL-2300 RA Leiden, Netherlands

[2] Leiden Univ, Med Ctr, NL-2300 RA Leiden, Netherlands

来源：

NEUROBIOLOGY OF AGING | 2003年 / 24卷

关键词：

stress; brain development; aging; hippocampus; hormones; glucocorticoids; glucocorticoid receptors;

D O I：

10.1016/S0197-4580(03)00057-5

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Data are emerging that the altered development of adrenocortical and emotional reactivity in individuals exposed perinatally to adverse events is reflected in cognitive change and that maternal care is an important determinant. However, early trauma does not cause a generalized cognitive decline at older age, but rather drives cognitive performance to the extremes, at the expense of the average performance demonstrated by normally reared individuals. (C) 2003 Elsevier Science Inc. All rights reserved.

引用

页码：S61 / S65

页数：5

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