The human adipose tissue is a source of multipotent stem cells

被引：288

作者：

Rodriguez, AM ^{[1
]}

Elabd, C ^{[1
]}

Amri, EZ ^{[1
]}

Ailhaud, G ^{[1
]}

Dani, C ^{[1
]}

机构：

[1] Fac Sci, Inst Rech Signalisat, Ctr Biochim, UMR 6543, F-06108 Nice, France

来源：

BIOCHIMIE | 2005年 / 87卷 / 01期

关键词：

embryonic stem cells; adult stem cell; adipose tissue;

D O I：

10.1016/j.biochi.2004.11.007

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Multipotent stem cells constitute an unlimited source of differentiated cells that could be used in pharmacological studies and in medicine. Recently, several publications have reported that adipose tissue contains a population of cells able to differentiate into different cell types including adipocytes, osteoblasts, myoblasts, and chondroblasts. More recently, stem cells with a multi-lineage potential at the single cell level have been isolated from human adipose tissue. These cells, called human Multipotent Adipose-Derived Stem (hMADS) cells, have been established in culture and interestingly, maintain their characteristics with long-term passaging. The adipocyte differentiation of hMADS cells has been thoroughly studied and differentiated cells exhibit the unique feature of human adipocytes. Finally, potential applications of stem cells isolated from adipose tissue in medicine will be discussed. (c) 2004 Elsevier SAS. All rights reserved.

引用

页码：125 / 128

页数：4

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