Aurora A: Target invalidated?

被引：9

作者：

Cochran, Andrea G. ^{[1
]}

机构：

[1] Genentech Inc, Dept Prot Engn, San Francisco, CA 94080 USA

来源：

CHEMISTRY & BIOLOGY | 2008年 / 15卷 / 06期

关键词：

D O I：

10.1016/j.chembiol.2008.06.002

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Aurora kinases are important mitotic regulators, and Aurora kinase inhibitors are under investigation as treatments for cancer. An ongoing debate in the field is which Aurora kinase is the better drug target. A new study (Girdler et al., 2008, in this issue of Chemistry & Biology) pushes the case forward for Aurora B.

引用

页码：525 / 526

页数：2

共 11 条

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