Spiral-path high-sensitivity silicon photonic wire molecular sensor with temperature-independent response

被引:132
作者
Densmore, A. [1 ]
Xu, D. -X. [1 ]
Janz, S. [1 ]
Waldron, P. [1 ]
Mischki, T. [2 ]
Lopinski, G. [2 ]
Delage, A. [1 ]
Lapointe, J. [1 ]
Cheben, P. [1 ]
Lamontagne, B. [1 ]
Schmid, J. H. [1 ]
机构
[1] Natl Res Council Canada, Inst Microstruct Sci, Ottawa, ON K1A 0R6, Canada
[2] Natl Res Council Canada, Steacie Inst Mol Sci, Ottawa, ON K1A 0R6, Canada
关键词
D O I
10.1364/OL.33.000596
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We demonstrate a new silicon photonic wire waveguide evanescent field (PWEF) sensor that exploits the strong evanescent field of the transverse magnetic mode of this high-index-contrast, submicrometer-dimension waveguide. High sensitivity is achieved by using a 2 mm. long double-spiral waveguide structure that fits within a compact circular area of 150 mu m diameter, facilitating compatibility with commercial spotting apparatus and the fabrication of densely spaced sensor arrays. By incorporating the PWEF sensor element into a balanced waveguide Mach-Zehnder interferometer circuit, a minimum detectable mass of similar to 10 fg of streptavidin protein is demonstrated with near temperature-independent response. (C) 2008 Optical Society of America.
引用
收藏
页码:596 / 598
页数:3
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共 10 条
  • [1] Nanotaper for compact mode conversion
    Almeida, VR
    Panepucci, RR
    Lipson, M
    [J]. OPTICS LETTERS, 2003, 28 (15) : 1302 - 1304
  • [2] Label-free, single-molecule detection with optical microcavities
    Armani, Andrea M.
    Kulkarni, Rajan P.
    Fraser, Scott E.
    Flagan, Richard C.
    Vahala, Kerry J.
    [J]. SCIENCE, 2007, 317 (5839) : 783 - 787
  • [3] Biochemical sensors based on polymer microrings with sharp asymmetrical resonance
    Chao, CY
    Guo, LJ
    [J]. APPLIED PHYSICS LETTERS, 2003, 83 (08) : 1527 - 1529
  • [4] A silicon-on-insulator photonic wire based evanescent field sensor
    Densmore, A.
    Xu, D. X.
    Waldron, P.
    Janz, S.
    Cheben, P.
    Lapointe, J.
    Delage, A.
    Lamontagne, B.
    Schmid, J. H.
    Post, E.
    [J]. IEEE PHOTONICS TECHNOLOGY LETTERS, 2006, 18 (21-24) : 2520 - 2522
  • [5] Thin silicon waveguides for biological and chemical sensing - art. no. 647718
    Densmore, Adam
    Xu, Dan-Xia
    Waldron, Philip
    Janz, Siegfried
    Delfige, Andr
    Cheben, Pavel
    Lapointe, Jean
    [J]. Silicon Photonics II, 2007, 6477 : 47718 - 47718
  • [6] Protein absorption and ellipsometry in biomaterial research
    Elwing, H
    [J]. BIOMATERIALS, 1998, 19 (4-5) : 397 - 406
  • [8] An integrated optical interferometric nanodevice based on silicon technology for biosensor applications
    Prieto, F
    Sepúlveda, B
    Calle, A
    Llobera, A
    Domínguez, C
    Abad, A
    Montoya, A
    Lechuga, LM
    [J]. NANOTECHNOLOGY, 2003, 14 (08) : 907 - 912
  • [9] Optical biosensor microsystems based on the integration of highly sensitive Mach-Zehnder interferometer devices
    Sepulveda, B.
    Sanchez del Rio, J.
    Moreno, M.
    Blanco, F. J.
    Mayora, K.
    Dominguez, C.
    Lechuga, L. M.
    [J]. JOURNAL OF OPTICS A-PURE AND APPLIED OPTICS, 2006, 8 (07): : S561 - S566
  • [10] The density and refractive index of adsorbing protein layers
    Vörös, J
    [J]. BIOPHYSICAL JOURNAL, 2004, 87 (01) : 553 - 561