ProSight PTM 2.0: improved protein identification and characterization for top down mass spectrometry

被引:195
作者
Zamdborg, Leonid [1 ]
LeDuc, Richard D. [1 ]
Glowacz, Kevin J. [1 ]
Kim, Yong-Bin [1 ]
Viswanathan, Vinayak [1 ]
Spaulding, Ian T. [1 ]
Early, Bryan P. [1 ]
Bluhm, Eric J. [1 ]
Babai, Shannee [1 ]
Kelleher, Neil L. [1 ]
机构
[1] Univ Illinois, Dept Chem, Urbana, IL 61801 USA
关键词
D O I
10.1093/nar/gkm371
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
ProSight PTM 2.0 (http://prosightptm2.scs.uiuc.edu) is the next generation of the ProSight PTM web-based system for the identification and characterization of proteins using top down tandem mass spectrometry. It introduces an entirely new data-driven interface, integrated Sequence Gazer for protein characterization, support for fixed modifications, terminal modifications and improved support for multiple precursor ions (multiplexing). Furthermore, it supports data import and export for local analysis and collaboration.
引用
收藏
页码:W701 / W706
页数:6
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