Dienogest, a new conservative strategy for extragenital endometriosis: a pilot study

被引：35

作者：

Harada, Miyuki ^{[1
]}

Osuga, Yutaka ^{[1
]}

Izumi, Gentaro ^{[1
]}

Takamura, Masashi ^{[1
]}

Takemura, Yuri ^{[1
]}

Hirata, Tetsuya ^{[1
]}

Yoshino, Osamu ^{[1
]}

Koga, Kaori ^{[1
]}

Yano, Tetsu ^{[1
]}

Taketani, Yuji ^{[1
]}

机构：

[1] Univ Tokyo, Dept Obstet & Gynecol, Fac Med, Bunkyo Ku, Tokyo 1138655, Japan

来源：

GYNECOLOGICAL ENDOCRINOLOGY | 2011年 / 27卷 / 09期

关键词：

Endometriosis; extragenital endometriosis; dienogest; conservative therapy; LONG-TERM USE; MULTICENTER; SYMPTOMS; ACETATE;

D O I：

10.3109/09513590.2010.533800

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Extragenital endometriosis severely impairs the quality of life for affected women but its standard management has not yet been well established because of its relatively low incidence. As extragenital organs, intestine, followed by urinary tract, is the most common place affected by endometriosis, for which surgical treatment is sometimes difficult and accompanied by severe complications. Recently, dienogest, a novel progestin, has emerged as a new alternative for endometriosis, especially for endometriosis-associated pain. In this report, we presented four cases with rectosigmoidal and one with bladder endometriosis, treated with oral 2 mg/day dienogest for over 6 months. For all cases, the measurable extragenital lesions exhibited the reduction in their size after 10 to 11 months of use, accompanied with immediate relief of subjective symptoms related with extragenital lesions. This report suggests that dienogest can be a novel conservative alternative for extragenital endometriosis.

引用

页码：717 / 720

页数：4

共 16 条

[1]

DIFFERENT TYPES OF EXTRAGENITAL ENDOMETRIOSIS - A REVIEW [J].