Surface plasmon resonance: towards an understanding of the mechanisms of biological molecular recognition

被引：321

作者：

McDonnell, JM ^{[1
]}

机构：

[1] Univ Oxford, Dept Biochem, Mol Biophys Lab, Oxford OX1 3QU, England

来源：

CURRENT OPINION IN CHEMICAL BIOLOGY | 2001年 / 5卷 / 05期

关键词：

D O I：

10.1016/S1367-5931(00)00251-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

With the introduction of new instruments and improved sensor chip chemistries, surface plasmon resonance (SPR) is finding new applications for molecular interaction studies. Easy access to high-quality kinetic and thermodynamic data for macromolecular binding events is providing insights into the fundamental mechanisms of molecular recognition. Progress is being made to allow larger-scale interaction studies. In addition, combining SPR with other analytical methods is enabling SPR-based analysis of interaction proteomics.

引用

页码：572 / 577

页数：6

共 63 条

[1] Application of surface plasmon resonance toward studies of low-molecular-weight antigen-antibody binding interactions [J].

Adamczyk, M ;

Moore, JA ;

Yu, ZG .

METHODS-A COMPANION TO METHODS IN ENZYMOLOGY, 2000, 20 (03) :319-328

[2]

Andersson K, 1999, PROTEINS, V37, P494, DOI 10.1002/(SICI)1097-0134(19991115)37:3<494::AID-PROT16>3.0.CO

[3]

2-F

[4]

ATKINS P, 2001, ELEMENTS PHYSICAL CH

[5] Electrostatic dependence of the thrombin-thrombomodulin interaction [J].

Baerga-Ortiz, A ;

Rezaie, AR ;

Komives, EA .

JOURNAL OF MOLECULAR BIOLOGY, 2000, 296 (02) :651-658

[6] Surface plasmon resonance imaging measurements of ultrathin organic films [J].

Brockman, JM ;

Nelson, BP ;

Corn, RM .

ANNUAL REVIEW OF PHYSICAL CHEMISTRY, 2000, 51 :41-63

[7] Structure and function of a membrane-bound murine MHC class I molecule [J].

Celia, H ;

Wilson-Kubalek, E ;

Milligan, RA ;

Teyton, L .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (10) :5634-5639

[8] Identification of contact residues in the IgE binding site of human FcεRIα [J].

Cook, JPD ;

Henry, AJ ;

McDonnell, JM ;

Owens, RJ ;

Sutton, BJ ;

Gould, HJ .

BIOCHEMISTRY, 1997, 36 (50) :15579-15588

[9] SPR biosensor studies of the direct interaction between 27 drugs and a liposome surface:: Correlation with fraction absorbed in humans [J].

Danelian, E ;

Karlén, A ;

Karlsson, R ;

Winiwarter, S ;

Hansson, A ;

Löfås, S ;

Lennernäs, H ;

Hämäläinen, MD .

JOURNAL OF MEDICINAL CHEMISTRY, 2000, 43 (11) :2083-2086

[10] Determination of the refractive index increments of small molecules for correction of surface plasmon resonance data [J].

Davis, TM ;

Wilson, WD .

ANALYTICAL BIOCHEMISTRY, 2000, 284 (02) :348-353

← 1 2 3 4 5 6 7 →